Tag Archives: pectus excavatum etiology

What causes Pectus Excavatum?

There is currently no known cause of Pectus Excavatum (PE). Several ideas have been hypothesized, but none are fully supported by data: 1. Intrauterine compression, rickets, pulmonary restriction, diaphragm alterations resulting in posterior traction on the sternum, and failure of osteogenesis or chondrogenesis. 2. Overgrowth of costal cartilage (this is the current prevailing theory). Even… Read More »